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Cocco M, Pellegrini C, Martínez-Banaclocha H, Giorgis M, Marini E, Costale A, Miglio G, Fornai M, Antonioli L, López-Castejón G, Tapia-Abellán A, Angosto D, Hafner-Bratkovič I, Regazzoni L, Blandizzi C, Pelegrín P, Bertinaria M. Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease. J Med Chem. 2017 May 11;60(9):3656-3671. doi: 10.1021/acs.jmedchem.6b01624. Epub 2017 Apr 24. PubMed PMID: 28410442.
AÑO: 2017; IF: 6.253
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28410442
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Hafner-Bratkovič I, Sušjan P, Lainšček D, Tapia-Abellán A, Cerović K, Kadunc L, Angosto-Bazarra D, Pelegrin P, Jerala R. NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway. Nat Commun. 2018 Dec 5;9(1):5182. doi: 10.1038/s41467-018-07573-4. PubMed PMID: 30518920; PubMed Central PMCID: PMC6281599.
AÑO: 2018; IF: 11.878
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Tapia-Abellan A, Angosto-Bazarra D, Martinez-Banaclocha H, de Torre-Minguela C, Ceron-Carrasco JP, Perez-Sanchez H, Arostegui JI, Pelegrin P. MCC950 closes the active conformation of NLRP3 to an inactive state. Nat Chem Biol. 2019 Jun;15(6):560-564. doi: 10.1038/s41589-019-0278-6. Epub 2019 May 13. Erratum In: Nat Chem Biol. 2021 Mar;17(3):361. PubMed PMID: 31086329; PubMed Central PMCID: PMC7116292.
AÑO: 2019; IF: 12.587
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Baroja-Mazo A, Compan V, Martin-Sanchez F, Tapia-Abellan A, Couillin I, Pelegrin P. Early endosome autoantigen 1 regulates IL-1beta release upon caspase-1 activation independently of gasdermin D membrane permeabilization. Sci Rep. 2019 Apr 8;9(1):5788. doi: 10.1038/s41598-019-42298-4. Erratum In: Sci Rep. 2020 Dec 1;10(1):21356. PubMed PMID: 30962463; PubMed Central PMCID: PMC6453936.
AÑO: 2019; IF: 4.996
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Ruiz-Alcaraz AJ, Martinez-Banaclocha H, Marin-Sanchez P, Carmona-Martinez V, Iniesta-Albadalejo MA, Tristan-Manzano M, Tapia-Abellan A, Garcia-Penarrubia P, Machado-Linde F, Pelegrin P, Martinez-Esparza M. Isolation of functional mature peritoneal macrophages from healthy humans. Immunol Cell Biol. 2020 Feb;98(2):114-126. doi: 10.1111/imcb.12305. Epub 2019 Dec 6. PubMed PMID: 31709677.
AÑO: 2020; IF: 5.853
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